Other Ways of Treating Erectile Dysfunction
As far as the inability of males to sustain penile erection is concerned, or what we call impotence / erectile dysfunction, there are treatments that are made to correct an imbalance that may happen in male sex hormones. Male hormone imbalance can do contribute to E.D. or erectile dysfunction. Cases of significantly low levels of testosterone, often resulting from a abnormality of this organ at birth or from trauma or blood vessel injury to the testes, can be corrected with intramuscular injections of the hormone or daily application of transdermal skin patches. This is administered every after 30 days. Hyperprolactinemia can also cause the condition. It is an oversecretion of the hormone prolactin caused by some tumor in the brain (specifically pituitary gland), can be medicated with the drug bromocriptine or by surgical removal of the pituitary gland. Take note though, that every after removal of the pituitary gland, the doctor may prescribe pituitary hormones as this must be supplemented after surgery.
Utilizing expernal agents like medicated creams for various types of erectile dysfunction, though not very effective in the past, is now undergoing clinical study. These vasodilating (or blood pooling) creams do not seem to show much promise, however, because the medications probably need to enter the blood streem itself to achieve a practical effect.
The pharmaceutical company that makes Viagra, named Pfizer, is exploring a lot of new ways of giving the drug, such as nasal and wafer delivery systems that may allow for a faster effect. This can cut down the the waiting time for an erection. Meanwhile other health experts are testing different oral medications. A medication named apomorphine, which stimulates the hypothalamus of the brain to signal the penis to erect, is being tested in the form of a tablet that dissolves in the mouth—an attempt to minimize its main side effects of nausea and vomiting. Phentolamine, currently used as a stand-alone and combination injectable drug, is also being tested in an oral form.
Going to genetics, we have gene therapy. It represents a new area of Erectile dysfunction research, one for which the penis is particularly well suited. Because the penis is external and easily accessible, a tourniquet can be easily tied (for up to 10 minutes) to prevent any injected genes or DNA from entering the general circulation. In addition, vascular smooth muscle cells, the probable targets for many gene therapies, have a low turnover rate, increasing the chances for the effects of the therapy to last for weeks or months. DNA therapy can be used in a lot of ways, including the insertion of genes into penile cells to produce proteins that are lacking because of missing or defective genes. Injected genes could also generate proteins that would make the penis more sensitive to compensate for an organic disorder.
A couple of gene therapy approaches are currently being studied. This is what Jacob Rajfer of the University of California at Los Angeles Medical Center is aiming to do. He is attempting to introduce a precursor gene into the penis to boost nitric oxide production when the gene is activated by a chemical stimulant. The potential for a healthy, satisfactory therapy in humans that would allow spontaneous erections is truly promising and will be brought to clinical testing a few years from now.
















5 out of 5

